Professor, Flasgship Director
University of Eastern Finland
Research line: Gene, Cell, Clinical
Role in project: Development of new gene drugs, translational research
Professor Ylä-Herttuala runs a world leading laboratory in cardiovascular and malignant glioma gene therapy. Main focus of the research is on the development of new gene drugs, translational research and phase I/II human clinical trials.
The main focus of the research is on the development of new gene therapy approaches for cardiovascular diseases, malignant glioma and diseases caused by disturbances in vascular biology. Virus-derived gene transfer vectors, cloning of new treatment genes and the use of genetic information for therapeutic purposes form the main research activities in the group. Also, translational research and clinical phase I/II human studies are conducted with vectors and treatment genes developed in the group. So far, we have conducted eight phase I/II/III clinical studies with vectors developed and produced in the National Virus Vector Laboratory located in A.I. Virtanen Institute, University of Eastern Finland.