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Winiarczyk, M., D. Winiarczyk, K. Michalak, K. Kaarniranta, Ł. Adaszek, S. Winiarczyk, and J. Mackiewicz. Dysregulated Tear Film Proteins in Macular Edema Due to the Neovascular Age-Related Macular Degeneration Are Involved in the Regulation of Protein  Clearance, Inflammation, and Neovascularization. Journal of Clinical Medicine, vol. 10, no. 14, July 2021, https://doi.org/10.3390/jcm10143060.

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Liuska, P. J., S. Lemmelä, A. S. Havulinna, K. Kaarniranta, H. Uusitalo, H. Laivuori, T. Kiiskinen, M. J. Daly, A. Palotie, and J. A. Turunen. Association of the MYOC p.(Gln368Ter) Variant With Glaucoma in a Finnish Population. JAMA Ophthalmology, vol. 139, no. 7, July 2021, pp. 762–68, https://doi.org/10.1001/jamaophthalmol.2021.1610.

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Wedenoja, J., J. Kalsi, S. Salenius, K. Parkkari, K. Kaarniranta, and T. Tervo. The Role of Vision-Related Problems in Fatal Road Accidents in Finland. Acta Ophthalmologica, vol. 99, no. 4, June 2021, pp. 427–30, https://doi.org/10.1111/aos.14616.

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Bhattarai, N., E. Korhonen, Y. Mysore, K. Kaarniranta, and A. Kauppinen. Hydroquinone Induces NLRP3-Independent IL-18 Release from ARPE-19 Cells. Cells, vol. 10, no. 6, June 2021, https://doi.org/10.3390/cells10061405.

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Mushimiyimana, I., V. Tomas Bosch, H. Niskanen, N. L. Downes, P. R. Moreau, K. Hartigan, S. Ylä-Herttuala, N. Laham-Karam, and M. U. Kaikkonen. Genomic Landscapes of Noncoding RNAs Regulating VEGFA and VEGFC Expression in Endothelial Cells. Molecular and Cellular Biology, vol. 41, no. 7, June 2021, p. e0059420, https://doi.org/10.1128/MCB.00594-20.

Zini, J., J. Kekkonen, V. A. Kaikkonen, T. Laaksonen, P. Keränen, T. Talala, A. J. Mäkynen, M. Yliperttula, and I. Nissinen. Drug Diffusivities in Nanofibrillar Cellulose Hydrogel by Combined Time-Resolved Raman and Fluorescence Spectroscopy. Journal of Controlled Release : Official Journal of the Controlled Release Society, vol. 334, June 2021, pp. 367–75, https://doi.org/10.1016/j.jconrel.2021.04.032.

Zięba, A., T. Laitinen, J. Z. Patel, A. Poso, and A. A. Kaczor. Docking-Based 3D-QSAR Studies for 1,3,4-Oxadiazol-2-One Derivatives as FAAH Inhibitors. International Journal of Molecular Sciences, vol. 22, no. 11, June 2021, https://doi.org/10.3390/ijms22116108.

Hytti, M., E. Korhonen, H. Hongisto, K. Kaarniranta, H. Skottman, and A. Kauppinen. Differential Expression of Inflammasome-Related Genes in Induced Pluripotent Stem-Cell-Derived Retinal Pigment Epithelial Cells with or without History of  Age-Related Macular Degeneration. International Journal of Molecular Sciences, vol. 22, no. 13, June 2021, https://doi.org/10.3390/ijms22136800.

Gulumkar, V., A. Äärelä, O. Moisio, J. Rahkila, V. Tähtinen, L. Leimu, N. Korsoff, H. Korhonen, P. Poijärvi-Virta, S. Mikkola, V. Nesati, E. Vuorimaa-Laukkanen, T. Viitala, M. Yliperttula, A. Roivainen, and P. Virta. Controlled Monofunctionalization of Molecular Spherical Nucleic Acids on a Buckminster Fullerene Core. Bioconjugate Chemistry, vol. 32, no. 6, June 2021, pp. 1130–38, https://doi.org/10.1021/acs.bioconjchem.1c00187.

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Ranta-Aho, S., N. Piippo, E. Korhonen, K. Kaarniranta, M. Hytti, and A. Kauppinen. TAS-116, a Well-Tolerated Hsp90 Inhibitor, Prevents the Activation of the NLRP3 Inflammasome in Human Retinal Pigment Epithelial Cells. International Journal of Molecular Sciences, vol. 22, no. 9, May 2021, https://doi.org/10.3390/ijms22094875.

Kicková, E., S. Salmaso, F. Mastrotto, P. Caliceti, and A. Urtti. Pullulan Based Bioconjugates for Ocular Dexamethasone Delivery. Pharmaceutics, vol. 13, no. 6, May 2021, https://doi.org/10.3390/pharmaceutics13060791.

Balla, A., S. Auriola, A. C. Grey, N. J. Demarais, A. Valtari, E. M. Heikkinen, E. Toropainen, A. Urtti, K.-S. Vellonen, and M. Ruponen. Partitioning and Spatial Distribution of Drugs in Ocular Surface Tissues. Pharmaceutics, vol. 13, no. 5, May 2021, https://doi.org/10.3390/pharmaceutics13050658.

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Wang, L., S. Poque, K. Laamanen, J. Saarela, A. Poso, T. Laitinen, and J. P. T. Valkonen. In Vitro Identification and In Vivo Confirmation of Inhibitors for Sweet Potato Chlorotic Stunt Virus RNA Silencing Suppressor, a Viral RNase III. Journal of Virology, vol. 95, no. 12, May 2021, https://doi.org/10.1128/JVI.00107-21.

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Zhang, J., T. Furuta, H. Sabit, S. Tamai, S. Jiapaer, Y. Dong, M. Kinoshita, Y. Uchida, S. Ohtsuki, T. Terasaki, S. Zhao, and M. Nakada. Gelsolin Inhibits Malignant Phenotype of Glioblastoma and Is Regulated by MiR-654-5p and MiR-450b-5p. Cancer Science, vol. 111, no. 7, July 2020, pp. 2413–22, https://doi.org/10.1111/cas.14429.

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Uchida, Y., H. Sasaki, and T. Terasaki. Establishment and Validation of Highly Accurate Formalin-Fixed Paraffin-Embedded Quantitative Proteomics by Heat-Compatible Pressure Cycling Technology Using  Phase-Transfer Surfactant and SWATH-MS. Scientific Reports, vol. 10, no. 1, July 2020, p. 11271, https://doi.org/10.1038/s41598-020-68245-2.

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Jaakkola, S., I. Nuotio, J. E. K. Hartikainen, and K. E. J. Airaksinen. Early Cardioversion for Acute Atrial Fibrillation in Low Stroke Risk Patients Is Safe Without Anticoagulation. Journal of the American College of Cardiology, vol. 76, no. 2, July 2020, pp. 226–27, https://doi.org/10.1016/j.jacc.2020.04.076.

Hoshi, Y., Y. Uchida, T. Kuroda, M. Tachikawa, P.-O. Couraud, T. Suzuki, and T. Terasaki. Distinct Roles of Ezrin, Radixin and Moesin in Maintaining the Plasma Membrane Localizations and Functions of Human Blood-Brain Barrier Transporters. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism, vol. 40, no. 7, July 2020, pp. 1533–45, https://doi.org/10.1177/0271678X19868880.

Kaarniranta, K., E. Pawlowska, J. Szczepanska, and J. Blasiak. DICER1 in the Pathogenesis of Age-Related Macular Degeneration (AMD) – Alu RNA Accumulation versus MiRNA Dysregulation. Aging and Disease, vol. 11, no. 4, July 2020, pp. 851–62, https://doi.org/10.14336/AD.2019.0809.

Ramsay, E., M. Raviña, S. Sarkhel, S. Hehir, N. R. Cameron, T. Ilmarinen, H. Skottman, J. Kjems, A. Urtti, M. Ruponen, and A. Subrizi. Avoiding the Pitfalls of SiRNA Delivery to the Retinal Pigment Epithelium with Physiologically Relevant Cell Models. Pharmaceutics, vol. 12, no. 7, July 2020, https://doi.org/10.3390/pharmaceutics12070667.

Laitinen, T., I. V. Baranovsky, L. S. Konstantinova, A. Poso, O. A. Rakitin, and C. R. M. Asquith. Antimicrobial and Antifungal Activity of Rare Substituted 1,2,3-Thiaselenazoles and Corresponding Matched Pair 1,2,3-Dithiazoles. Antibiotics (Basel, Switzerland), vol. 9, no. 7, July 2020, https://doi.org/10.3390/antibiotics9070369.

Heikkinen, E. M., M. Ruponen, L.-M. Jasper, J. Leppänen, L. Hellinen, A. Urtti, S. Auriola, J. Rautio, and K.-S. Vellonen. Prodrug Approach for Posterior Eye Drug Delivery: Synthesis of Novel Ganciclovir Prodrugs and in Vitro Screening with Cassette Dosing. Molecular Pharmaceutics, vol. 17, no. 6, June 2020, pp. 1945–53, https://doi.org/10.1021/acs.molpharmaceut.0c00037.

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Hellinen, L., S. Bahrpeyma, A.-K. Rimpelä, M. Hagström, M. Reinisalo, and A. Urtti. Microscale Thermophoresis as a Screening Tool to Predict Melanin Binding of Drugs. Pharmaceutics, vol. 12, no. 6, June 2020, https://doi.org/10.3390/pharmaceutics12060554.

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Korhonen, E., N. Piippo, M. Hytti, J. M. T. Hyttinen, K. Kaarniranta, and A. Kauppinen. Only IL-1β Release Is Inflammasome-Dependent upon Ultraviolet B Irradiation Although IL-18 Is Also Secreted. FASEB Journal, vol. 34, no. 5, May 2020, pp. 6437–48, https://doi.org/10.1096/fj.201902355RR.

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Salminen, A., K. Kaarniranta, and A. Kauppinen. ER Stress Activates Immunosuppressive Network: Implications for Aging and Alzheimer’s Disease. Journal of Molecular Medicine (Berlin, Germany), vol. 98, no. 5, May 2020, pp. 633–50, https://doi.org/10.1007/s00109-020-01904-z.

Laihia, J., R. Järvinen, E. Wylęgała, and K. Kaarniranta. Disease Aetiology-Based Design of Multifunctional Microemulsion Eye Drops for Moderate or Severe Dry Eye: A Randomized, Quadruple-Masked and Active-Controlled  Clinical Trial. Acta Ophthalmologica, vol. 98, no. 3, May 2020, pp. 244–54, https://doi.org/10.1111/aos.14252.

Taipale, C., J.-M. Lindholm, K. Kaarniranta, and R. Tuuminen. Comparison of Two Different Treat-and-Extend Protocols with Aflibercept in Wet Age-Related Macular Degeneration: Two-Year Results. Advances in Therapy, vol. 37, no. 5, May 2020, pp. 2256–66, https://doi.org/10.1007/s12325-020-01312-2.

Korhonen, E., J. Bisevac, J. M. T. Hyttinen, N. Piippo, M. Hytti, K. Kaarniranta, G. Petrovski, and A. Kauppinen. UV-B-Induced Inflammasome Activation Can Be Prevented by Cis-Urocanic Acid in Human Corneal Epithelial Cells. Investigative Ophthalmology & Visual Science, vol. 61, no. 4, Apr. 2020, p. 7, https://doi.org/10.1167/iovs.61.4.7.

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Salonius, E., L. Kontturi, A. Laitinen, A.-M. Haaparanta, M. Korhonen, J. Nystedt, I. Kiviranta, and V. Muhonen. Chondrogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stromal Cells in a Three-Dimensional Environment. Journal of Cellular Physiology, vol. 235, no. 4, Apr. 2020, pp. 3497–507, https://doi.org/10.1002/jcp.29238.

Bhattarai, N., E. Korhonen, M. Toppila, A. Koskela, K. Kaarniranta, Y. Mysore, and A. Kauppinen. Resvega Alleviates Hydroquinone-Induced Oxidative Stress in ARPE-19 Cells. International Journal of Molecular Sciences, vol. 21, no. 6, Mar. 2020, https://doi.org/10.3390/ijms21062066.

Sridevi Gurubaran, I., J. Viiri, A. Koskela, J. M. T. Hyttinen, J. J. Paterno, G. Kis, M. Antal, A. Urtti, A. Kauppinen, S. Felszeghy, and K. Kaarniranta. Mitophagy in the Retinal Pigment Epithelium of Dry Age-Related Macular Degeneration Investigated in the NFE2L2/PGC-1α(-/-) Mouse Model. International Journal of Molecular Sciences, vol. 21, no. 6, Mar. 2020, https://doi.org/10.3390/ijms21061976.

Amirkavei, M., M. Pitkänen, O. Kaikkonen, K. Kaarniranta, H. André, and A. Koskelainen. Induction of Heat Shock Protein 70 in Mouse RPE as an In Vivo Model of Transpupillary Thermal Stimulation. International Journal of Molecular Sciences, vol. 21, no. 6, Mar. 2020, https://doi.org/10.3390/ijms21062063.

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Josifovska, N., R. Albert, R. Nagymihály, L. Lytvynchuk, M. C. Moe, K. Kaarniranta, Z. J. Veréb, and G. Petrovski. Resveratrol as Inducer of Autophagy, Pro-Survival, and Anti-Inflammatory Stimuli in Cultured Human RPE Cells. International Journal of Molecular Sciences, vol. 21, no. 3, Jan. 2020, https://doi.org/10.3390/ijms21030813.

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