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Ullah MS, Zhivonitko VV, Samoylenko A, Zhyvolozhnyi A, Viitala S, Kankaanpää S, Komulainen S, Schröder L, Vainio SJ, Telkki VV. Identification of extracellular nanoparticle subsets by nuclear magnetic resonance. Chem Sci. 2021 Apr 29;12(24):8311-8319.

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Bart G, Fischer D, Samoylenko A, Zhyvolozhnyi A, Stehantsev P, Miinalainen I, Kaakinen M, Nurmi T, Singh P, Kosamo S, Rannaste L, Viitala S, Hiltunen J, Vainio SJ. Characterization of nucleic acids from extracellular vesicle-enriched human sweat. BMC Genomics. 2021 Jun 9;22(1):425.

doi: 10.1186/s12864-021-07733-9.


Monteiro-Reis S, Carvalho-Maia C, Bart G, Vainio SJ, Pedro J, Silva ER, Sales G, Henrique R, Jerónimo C. Secreted Extracellular Vesicle Molecular Cargo as a Novel Liquid Biopsy Diagnostics of Central Nervous System Diseases. Int J Mol Sci. 2021 Mar 23;22(6):3267.

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Andjus P, Kosanović M, Milićević K, Gautam M, Vainio SJ, Jagečić D, Kozlova EN, Pivoriūnas A, Chachques JC, Sakaj M, Brunello G, Mitrecic D, Zavan B. Extracellular Vesicles as Innovative Tool for Diagnosis, Regeneration and Protection against Neurological Damage. Int J Mol Sci. 2020 Sep 18;21(18):6859.

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Rilla K. Diverse plasma membrane protrusions act as platforms for extracellular vesicle shedding. J Extracell Vesicles. 2021 Sep;10(11):e12148.

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The power of imaging to understand extracellular vesicle biology in vivo | Nature Methods


S. Balasubramaniam S, Barros M. T, Veletić M, Kanada M, Pierobon M, Vainio S, Balasingham I. Editorial—Special Issue on Molecular Communications for Diagnostics and Therapeutic Development of Infectious Diseases. IEEE Transactions on Molecular, Biological and Multi-Scale Communications, vol. 7, no. 3, pp. 117-120, Sept. 2021.

Editorial—Special Issue on Molecular Communications for Diagnostics and Therapeutic Development of Infectious Diseases | IEEE Journals & Magazine | IEEE Xplore


Abou-Hassan A, Barros A, Buchholz N, Carugo D, Clavica F, de Graaf P, de La Cruz J, Kram W, Mergulhao F, Reis RL, Skovorodkin I, Soria F, Vainio S, Zheng S. Potential strategies to prevent encrustations on urinary stents and catheters – thinking outside the box: a European network of multidisciplinary research to improve urinary stents (ENIUS) initiative. Expert Rev Med Devices. 2021 Jun 11:1-9. doi: 10.1080/17434440.2021.1939010. Epub ahead of print.

https://doi.org/10.1080/17434440.2021.1939010


Tavakoli S, Kari OK, Turunen T, Lajunen T, Schmitt M, Lehtinen J, Tasaka F, Parkkila P, Ndika J, Viitala T, Alenius H, Urtti A, Subrizi A. Diffusion and Protein Corona Formation of Lipid-Based Nanoparticles in the Vitreous Humor: Profiling and Pharmacokinetic Considerations. Mol Pharm. 2021 Feb 1;18(2):699-713. doi: 10.1021/acs.molpharmaceut.0c00411.

Keywords: lipid-based nanoparticle; ocular pharmacokinetics; protein corona; proteomics; single-particle tracking; vitreal diffusion.

https://pubs.acs.org/doi/10.1021/acs.molpharmaceut.0c00411


Kapiainen E, Kihlström MK, Pietilä R, Kaakinen M, Ronkainen VP, Tu H, Heikkinen A, Devarajan R, Miinalainen I, Laitakari A, Ansarizadeh M, Zhang Q, Wei GH, Ruddock L, Pihlajaniemi T, Elamaa H, Eklund L. The Amino-Terminal Oligomerization Domain of Angiopoietin-2 Affects Vascular Remodeling, Mammary Gland Tumor Growth, and Lung Metastasis in Mice. Cancer Res. 2021 Jan 1;81(1):129-143. doi: 10.1158/0008-5472.CAN-19-1904.

https://cancerres.aacrjournals.org/content/81/1/129.long


Ali N, Rezvani HR, Motei D, Suleman S, Mahfouf W, Marty I, Ronkainen VP, Vainio SJ. Trisk 95 as a novel skin mirror for normal and diabetic systemic glucose level. Sci Rep. 2020 Jul 22;10(1):12246. doi: 10.1038/s41598-020-68972-6.

https://www.nature.com/articles/s41598-020-68972-6


Gurvich OL, Puttonen KA, Bailey A, Kailaanmäki A, Skirdenko V, Sivonen M, Pietikäinen S, Parker NR, Ylä-Herttuala S, Kekarainen T. Transcriptomics uncovers substantial variability associated with alterations in manufacturing processes of macrophage cell therapy products. Sci Rep. 2020 Aug 20;10(1):14049. doi: 10.1038/s41598-020-70967-2.

https://www.nature.com/articles/s41598-020-70967-2


Adnan Awad S, Dufva O, Ianevski A, Ghimire B, Koski J, Maliniemi P, Thomson D, Schreiber A, Heckman CA, Koskenvesa P, Korhonen M, Porkka K, Branford S, Aittokallio T, Kankainen M, Mustjoki S. RUNX1 mutations in blast-phase chronic myeloid leukemia associate with distinct phenotypes, transcriptional profiles, and drug responses. Leukemia. 2020 Aug 11. doi: 10.1038/s41375-020-01011-5.

https://www.nature.com/articles/s41375-020-01011-5


Schenkwein D, Afzal S, Nousiainen A, Schmidt M, Ylä-Herttuala S. Efficient Nuclease-Directed Integration of Lentivirus Vectors into the Human Ribosomal DNA Locus. Mol Ther. 2020 Aug 5;28(8):1858-1875. doi: 10.1016/j.ymthe.2020.05.019.

Keywords: HIV-1 integrase; I-Ppl; all-in-one LV; genomic safe harbor site; lentivirus vector; meganuclease; protein transduction; ribosomal DNA; site-specific; targeted integration.

https://www.sciencedirect.com/science/article/pii/S1525001620302537?via%3Dihub


Saari H, Turunen T, Lõhmus A, Turunen M, Jalasvuori M, Butcher SJ, Ylä-Herttuala S, Viitala T, Cerullo V, Siljander PRM, Yliperttula M. Extracellular vesicles provide a capsid-free vector for oncolytic adenoviral DNA delivery. J Extracell Vesicles. 2020 Apr 17;9(1):1747206. doi: 10.1080/20013078.2020.1747206.

Keywords: DNA delivery; Extracellular vesicles; adenovirus; cancer therapy.

https://onlinelibrary.wiley.com/doi/10.1080/20013078.2020.1747206


Dufva O, Koski J, Maliniemi P, Ianevski A, Klievink J, Leitner J, Pölönen P, Hohtari H, Saeed K, Hannunen T, Ellonen P, Steinberger P, Kankainen M, Aittokallio T, Keränen MAI, Korhonen M, Mustjoki S. Integrated drug profiling and CRISPR screening identify essential pathways for CAR T-cell cytotoxicity. Blood. 2020 Feb 27;135(9):597-609. doi: 10.1182/blood.2019002121.

https://ashpublications.org/blood/article/135/9/597/429647/Integrated-drug-profiling-and-CRISPR-screening