Research line: Gene, Cell
Role in project: Designer lentivirus vectors
Sophisticated gene transfer tools (vectors) are key in making safe and efficient treatment of different inherited and acquired diseases possible with gene therapy. My background is in molecular biology and my expertise includes multilevel optimization of lentivirus vectors (LVs), genome-wide analysis of gene transfer-related genotoxicity, designer nucleases, nucleolar biology and designing chimeric antigen receptor molecules. I have invented modifications to LVs that importantly improved their major safety concern, uncontrolled integration, and enabled the delivery of desired proteins into target cells.